Methods Sera samples of non-occupational human from Shenyang and Chongqing areas were collected, and the concentration of PFOS and PFOA in serum were measured by High Performance Liquid Chromatography/ Mass Selective Detector ( HPLC/ MS-MIS). 方法采集沈阳和重庆地区无职业性PFOS和PFOA暴露人群血清,采用高压液相色谱-质谱仪联机系统测定血清中PFOS和PFOA含量。